3, 4-methylenedioxypyrovalerone (MDPV) Rapid Tests

The MDPV Rapid Test Cassette (Urine) is a rapid chromatographic immunoassay for the detection of 3,4–methylenedioxypyrovalerone in human urine at a cut-off concentration of 3000 ng/mL. This assay provides only a preliminary analytical test result. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrometry (GC/MS) is the preferred confirmatory method. Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used.


  • Description
  • Specifications
  • 3, 4-methylenedioxypyrovalerone (MDPV) is a psychoactive recreational drug with stimulant properties which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI). It was first developed in the 1960s by a team at Boehringer Ingelheim. MDPV remained an obscure stimulant until around 2004 when it was reportedly sold as a designer drug. The recreational use of MDPV in the USA has become more prevalent since late 2010 and it is now illegal in many states[1].Products labeled as bath salts containing MDPV were previously sold as recreational drugs in gas stations and convenience stores in the United States, similar to the marketing for Spice and K2 as incense. MDPV is the 3,4-methylenedioxy ring-substituted analog of the compound pyrovalerone, developed in the 1960s, which has been used for the treatment of chronic fatigue and as an anorectic, 

    but caused problems of abuse and dependence. However, despite its structural similarity, the effects of MDPV bear little resemblance to other methylenedioxy phenylalkylamine derivatives such as 3,4-methylenedioxy-N-methylamphetamine (MDMA), instead producing primarily stimulant effects with only mild entactogenic qualities.

    MDPV undergoes CYP450 2D6, 2C19, 1A2, and COMT phase 1 metabolism (liver) into methylcatechol and pyrrolidine, which in turn are glucuronated (uridine 5'-diphospho-glucuronosyltransferase) allowing it to be excreted by the kidneys, with only a small fraction of the metabolites being excreted into the stools. No free pyrrolidine will be detected in the urine.The MDPV Rapid Test Cassette (Urine) is a rapid urine screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of 3,4-methylenedioxypyrovalerone in urine. The MDPV Rapid Test Cassette (Urine) yields a positive result when 3,4-methylenedioxypyrovalerone in urine exceed 3000 ng/mL

    Order Information


    Cat. No.

    Product

    Specimen

    Format

    PackCut-off

    DMDP-S11

    MDPV Test Strip

    Urine

    Strip

    50T

    3000

    ng/ml

    DMDP-C11

    MDPV Test Cassette

    Urine

    Cassette

    25T

    DMDP-P11

    MDPV Test Panel

    Urine

    Panel

    25T



本网站由阿里云提供云计算及安全服务