Tricyclic Antidepressants (TCA) Rapid Tests

【SUMMARY】

TCA (Tricyclic Antidepressants) are commonly used for the treatment of depressive disorders. TCA overdoses can result in profound central nervous system depression, cardiotoxicity and anticholinergic effects. TCA overdose is the most common cause of death from prescription drugs. TCAs are taken orally and sometimes by injection. TCAs are metabolized in the liver, both TCAs and their metabolites are excreted in urine mostly in the form of metabolites for up to ten days.The TCA Rapid Test Cassette (Urine) is a rapid urine-screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of Nortriptyline in urine. The TCA Rapid Test Cassette (Urine) yields a positive result when the Nortriptyline in urine exceeds 1,000 ng/mL.

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