PRODUCTS
CONTACT US
Hangzhou Biotest Biotech Co., Ltd
Tel: International Regions
+86-571-89058016
North America/Latin America
+86-571-89058051
China
+86-571-89058000
Fax: +86-571-88633388
E-mail:info.support@biotests.com.cn
ADD: 17# Futai Road,Zhongtai Street, Yuhang District,
Hangzhou, China
Postal Code: 311121
Cotinine (COT) Rapid Tests
The COT Rapid Test is a rapid chromatographic immunoassay for the detection of Cotinine in human urine/saliva. This test will detect other related compounds, please refer to the Analytical Specificity table in this package insert.
- Description
- Specifications
-
【SUMMARY】
Cotinine is the first-stage metabolite of nicotine, a toxic alkaloid that produces stimulation of the autonomic ganglia and central nervous system when in humans. Nicotine is a drug to which virtually every member of a tobacco-smoking society is exposed whether through direct contact or second-hand inhalation. In addition to tobacco, nicotine is also commercially available as the active ingredient in smoking replacement therapies such as nicotine gum, transdermal patches and nasal sprays. In a 24-hour urine, approximately 5% of a nicotine dose is excreted as unchanged drug with 10% as cotinine and 35% as hydroxycotinine; the concentrations of other metabolites are believed to account for less than 5%.1 While cotinine is thought to be an inactive metabolite, it’s elimination profile is more stable than that of nicotine which is largely urine pH dependent. As a result, cotinine is considered a good biological marker for determining nicotine use. The plasma half-life of nicotine is approximately 60 minutes following inhalation or parenteral administration.2 Nicotine and cotinine are rapidly eliminated by the kidney; the window of detection for cotinine in urine at a cutoff level of 500 ng/mL is expected to be up to 2-3 days after nicotine use
【Order Information】
Cat. No.
Product
Specimen
Format
Pack Cut-off DCOT-S11
COT Test Strip
Urine
Strip
50T 100,
200,
ng/ml
DCOT-C11
COT Test Cassette
Urine
Cassette
25T DCOT-P11
COT Test Panel
Urine
Panel
25T DCOT-C81
COT Test Cassette
Saliva
Cassette
25T 30,50
ng/ml
Copyright©Hangzhou Biotest Biotech Co., LTD . All rights reserved. ICP:11051548-1 Powered by clouddream