Clozapine (CLZ) Rapid Tests

【SUMMARY】

Clozapine is an antipsychotic drug, structurally similar to olanzapine, that has been in use since 1989  for the treatment of severely ill schizophrenic patients who do not respond to standard antipsychotic  drug treatment. Clozapine is available as the free base in 25-100 mg tablets for oral administration.  Adverse reactions include hematologic, elevation of liver enzymes, seizures and tardive dyskinesia.  Clozapine is almost completely metabolized prior to excretion, undergoing N-demethylation, N- oxidation, oxidation of the chlorine-containing ring and thiomethyl conjugation. At least 80% of the  dose appears in the urine or feces as metabolites1

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